Nicotine Replacement Therapy Guide

Choosing NRT Dose

NRT dose is based on the number of cigarettes smoked daily and how dependent you are. Heavy smokers (20+ cigarettes/day): high-strength NRT (21mg patch, 4mg gum). Light to moderate (under 20/day): standard strength (14mg patch, 2mg gum). Fagerstrom Test for Nicotine Dependence: time to first cigarette is the strongest single indicator. First cigarette within 5 minutes indicates high physical dependence — use high-strength NRT regardless of daily cigarette count. Underdosing is a common reason NR

Patch vs Fast-Acting NRT

Patches: release nicotine slowly over 16 or 24 hours. Provide a stable baseline nicotine level, preventing withdrawal throughout the day. 24-hour patches: better for morning cravings. 16-hour patches: fewer sleep disturbances. Gum, lozenges, inhalator, nasal spray, mouth spray: fast-acting, used for breakthrough cravings. Combination NRT: patch provides baseline + fast-acting product for cravings. Combination NRT is approximately 30-40% more effective than single NRT. The NICE guideline recommen

How to Use NRT Effectively

Patches: apply to clean, dry, hairless skin — upper arm, chest, or back. Rotate sites daily to prevent skin irritation. Do not smoke while using a patch — nicotine overload risk (nausea, dizziness). Gum: chew-and-park technique — chew a few times until tingly, then park between cheek and gum for 30 seconds, then chew again. Do not swallow — nicotine is absorbed through the mouth lining, not the stomach. Duration: most guidelines recommend 8-12 weeks minimum. Stopping NRT too soon is a common cau

NRT vs Varenicline vs Bupropion

NRT: safest, available over-the-counter, effective (doubles quit rates vs placebo). Varenicline (Champix/Chantix): prescription only. Most effective pharmacological aid — 3× more effective than placebo, 1.5× more than NRT alone. Acts on nicotine receptors to reduce both withdrawal and the pleasure from smoking. Bupropion (Zyban): antidepressant that also reduces cravings — prescription only. 2× more effective than placebo. Combination of pharmacotherapy + behavioural support: most effective appr

Not medical advice. This calculator is for general information and education only. Figures are estimates and may not reflect your circumstances. For decisions, consult your GP or a qualified healthcare professional. See our editorial standards.

Nicotine Replacement Therapy (NRT) Dose Calculator

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